Field of Comparative Biomedical Sciences
Faculty Mentor: Dr. Volker Vogt
Current Position: Research Associate in the lab of Susan Weiss at the University of Pennsylvania
Judith Marie Phillips was born on May 26, 1979 in Ames, Iowa, an event that may have hastened the completion of her father's PhD. studies. She spent her childhood in Chester County, Pennsylvania, where she began her biology training by turning over rocks and identifying the creatures underneath. After graduating from Sanford School in Hockessin, Delaware, she attended Kenyon College, where she worked with professor Joan L. Slonczewski on pH-inducible genes in Escherichia coli and Helicobacter pylori before embarking on a senior thesis project with professor Elizabeth A. Ottinger on the binding of Src SH2 and SH3 domains to peptide analogs of the p130 Cas protein. Following her graduation from Kenyon in 2000, she thought that she had finished with research and entered the Cornell University College of Veterinary Medicine with the intention of going into private practice. The allure of the bench proved stronger than expected, and following a summer working with Dr. Kenneth Simpson on Helicobacter infection in cats as part of Cornell's Leadership Program for Veterinary Students, she enrolled in the newly-founded Dual D.V.M./Ph.D. program and joined the laboratory of professor Volker M. Vogt to study retrovirus assembly. She completed the D.V.M. program in 2006.
DVM/PhD, Cornell University
BA in Chemistry from Kenyon College
Publications & Presentations
Bush DL, Monroe EB, Bedwell GJ, Prevelige PE Jr, Phillips JM, Vogt VM. Higher-order structure of the Rous sarcoma virus SP assembly domain. J Virol. 2014 May;88(10):5617-29. doi: 10.1128/JVI.02659-13. Epub 2014 Mar 5. PubMed PMID: 24599998; PubMed Central PMCID: PMC4019137.
Zhao L, Birdwell LD, Wu A, Elliott R, Rose KM, Phillips JM, Li Y, Grinspan J, Silverman RH, Weiss SR. Cell-type-specific activation of the oligoadenylate synthetase-RNase L pathway by a murine coronavirus. J Virol. 2013 Aug;87(15):8408-18. doi: 10.1128/JVI.00769-13. Epub 2013 May 22. PubMed PMID: 23698313; PubMed Central PMCID: PMC3719824.
Phillips JM, Kuo IT, Richardson C, Weiss SR. A novel full-length isoform of murine pregnancy-specific glycoprotein 16 (psg16) is expressed in the brain but does not mediate murine coronavirus (MHV) entry. J Neurovirol. 2012 Apr;18(2):138-43. doi: 10.1007/s13365-012-0081-6. PubMed PMID: 22302612; PubMed Central PMCID: PMC3368079.
Phillips JM, Weiss SR. Pathogenesis of neurotropic murine coronavirus is multifactorial. Trends Pharmacol Sci. 2011 Jan;32(1):2-7. doi: 10.1016/j.tips.2010.11.001. Epub 2010 Dec 7. PubMed PMID: 21144598; PubMed Central PMCID: PMC3022387.
Bender SJ, Phillips JM, Scott EP, Weiss SR. Murine coronavirus receptors are differentially expressed in the central nervous system and play virus strain-dependent roles in neuronal spread. J Virol. 2010 Nov;84(21):11030-44. doi: 10.1128/JVI.02688-09. Epub 2010 Aug 25. PubMed PMID: 20739537; PubMed Central PMCID: PMC2953140.
de Marco A, Davey NE, Ulbrich P, Phillips JM, Lux V, Riches JD, Fuzik T, Ruml T, Kräusslich HG, Vogt VM, Briggs JA. Conserved and variable features of Gag structure and arrangement in immature retrovirus particles. J Virol. 2010 Nov;84(22):11729-36. doi: 10.1128/JVI.01423-10. Epub 2010 Sep 1. PubMed PMID: 20810738; PubMed Central PMCID: PMC2977881.
Phillips JM, Murray PS, Murray D, Vogt VM. A molecular switch required for retrovirus assembly participates in the hexagonal immature lattice. EMBO J. 2008 May 7;27(9):1411-20. doi: 10.1038/emboj.2008.71. Epub 2008 Apr 10. PubMed PMID: 18401344; PubMed Central PMCID: PMC2374847.
Slonczewski JL, McGee DJ, Phillips J, Kirkpatrick C, Mobley HL. pH-dependent protein profiles of Helicobacter pylori analyzed by two-dimensional gels. Helicobacter. 2000 Dec;5(4):240-7. PubMed PMID: 11179990.
Blankenhorn D, Phillips J, Slonczewski JL. Acid- and base-induced proteins during aerobic and anaerobic growth of Escherichia coli revealed by two-dimensional gel electrophoresis. J Bacteriol. 1999 Apr;181(7):2209-16. PubMed PMID: 10094700; PubMed Central PMCID: PMC93635.