Application of proteomics in various areas including: 
a) Diagnostic proteomics-Translational biomarkers to diagnose blood coagulation disorders of animal 
b) Meat science proteomics-Identification and evaluation of potential biomarkers of beef overall quality; Modelling/statistical approaches to predict the beef-eating qualities from farm-to-fork; 
The mechanisms and the bioinformatic analysis of meat tenderization 
c) Plants proteomics-the tolerance under heavy metal contamination

• PhD in Food Science and Technology, 2021, Teagasc Food Research Centre, Dublin, Ireland & University College Cork, Cork, Ireland
• MSc in Food Science and Engineering, 2016, Jinan University, Guangzhou, China
• BSc in Food Science and Engineering, 2013, Henan Agricultural University, Zhengzhou, China

• Postdoctoral researcher in College of Veterinary Medicine at Cornell University, one of the top research institutions in the world to expand the application of proteomics to animal health
• Extensive background of food science and technology specialist in meat science, combined with a solid knowledge foundation in food science, engineering and plant health, biochemistry, proteomics and bioinformatic analysis.
• Four-year structured PhD student at University College Cork sponsored by Walsh Fellowship in Teagasc | Agriculture and Food Development Authority, Ireland.

1. Lynch, A. M., Ruterbories, L. K., Zhu, Y., Fialkiewicz, F., Papich, M. G., Brooks, M. B., & Goggs, R. (2024). Comparison of the pharmacokinetics and pharmacodynamics of apixaban and rivaroxaban in dogs. Journal of Veterinary Internal Medicine, 38(6), 3242–3254.
2. Brooks, M. B., Brooks, J. C., Catalfamo, J., Zhu, Y., Goggs, R., Babasyan, S., Wagner, B., & LeVine, D. N. (2024). Plasma concentration of thrombopoietin in dogs with immune thrombocytopenia. Journal of Veterinary Internal Medicine, 38(5), 2507-2517.
3. Zhu, Y., Gagaoua, M., Mullen, A. M., Kelly, A. L. & Hamill, R. M. (2023). Molecular mechanisms contributing to the development of beef sensory texture and flavour traits and related biomarkers: Insights from early post-mortem muscle using label-free proteomics. Journal of proteomics, 286, 104953.
4. Hassine, S. B., Zhu, Y., Djebali, W., Sheehan, D, & Chaoui, A. (2023). Mitigation of copper toxicity by calcium and citrate involves the modulation of ascorbate-glutathione cycle and redox status in Pisum sativum L. seedlings. Journal of Soil Science and Plant Nutrition. (Submitted)
5. Gagaoua, M., & Zhu, Y. (2022). Chapter 6—Proteomics advances in beef production. In M. L. Pedrouso, D. F. Ruiz, & J. M. Lorenzo (Eds.), Food Proteomics (pp. 151–182). Academic Press.
6. Bartos, K., Ramakrishnan, S. K., Braga-Lagache, S., Hänzi, B., Durussel, F., Prakash Sridharan, A., Zhu, Y., Sheehan, D., Hynes, N. E., Bonny, O., & Moor, M. B. (2022). Renal FGF23 signaling depends on redox protein Memo1 and promotes orthovanadate-sensitive protein phosphotyrosyl phosphatase activity. Journal of Cell Communication and Signaling.
7. Zhu, Y., Gagaoua, M., Mullen, A. M., Viala, D., Rai, D. K., Kelly, A. L., Sheehan, D., & Hamill, R. M. (2021). Shotgun proteomics for the preliminary identification of biomarkers of beef sensory tenderness, juiciness and chewiness from plasma and muscle of young Limousin-sired bulls. Meat Science, 176, 108488.
8. Zhu, Y., Gagaoua, M., Mullen, A. M., Kelly, A. L., Sweeney, T., Cafferky, J., Viala, D., & Hamill, R. M. (2021). A Proteomic Study for the Discovery of Beef Tenderness Biomarkers and Prediction of Warner–Bratzler Shear Force Measured on Longissimus thoracis Muscles of Young Limousin- Sired Bulls. Foods, 10, 952.
9. Massoud, M. B., Kharbech, O., Sakouhi, L., Hassine, S. B., Zhu, Y., Chaoui, A., Sheehan, D., & Djebali, W. (2021). Calcium and Citrate Protect Pisum sativum Roots against Copper Toxicity by Regulating the Cellular Redox Status. Journal of Soil Science and Plant Nutrition, 22, 345–358.
10. Bartos, K., Ramakrishnan, S. K., Braga-Lagache, S., Hänzi, B., Durussel, F., Sridharan, A. P., Zhu, Y., Sheehan, D., Hynes, N. E., Bonny, O., & Moor, M. B. (2020). Redox protein Memo1 coordinates FGF23-driven signaling and small Rho-GTPases in the mouse kidney. BioRxiv, 2020.12.04.402511.
11. Zhu, Y., Mullen, A. M., Rai, D. K., Kelly, A. L., Sheehan, D., Cafferky, J., & Hamill, R. M. (2019). Assessment of RNAlater® as a Potential Method to Preserve Bovine Muscle Proteins Compared with Dry Ice in a Proteomic Study. Foods, 8(2), 60.
12. Massoud, M. B., Sakouhi, L., Karmous, I., Zhu, Y., El Ferjani, E., Sheehan, D., & Chaoui, A. (2018). Protective role of exogenous phytohormones on redox status in pea seedlings under copper stress. Journal of plant physiology, 221, 51-61.
13. Sheehan, D., Sridharan, A., Doyle, H., & Zhu, Y. (2016). Effects of metal oxide nanomaterials on cultured human cells: A redox proteomic investigation.
14. Zhu Y., Liu S., Zhang X. & Tang S. (2015) On-line Monitoring and Emergency Warning of Colchicine in Drinking Water by Using Flow-injection Chemiluminescence. Journal of Hunan Agricultural University (Natural Sciences), Oct. 2015, 41(5):538–543

Walsh Scholarship 2016022, Teagasc, 2016 to 2020