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Baker Institute Publications Fiscal Year 2023

June 2023

 

Mouncey RR, de Mestre AM, Arango-Sabogal JC, Verheyen KL. Early-life limb deformities in Thoroughbred foals and investigation of their associations with mare-and pregnancy-related factors. Journal of Equine Veterinary Science. 2023 June; 125:104812. 

 

DOI: 10.1016/j.jevs.2023.104812

 

 

Weldon PW, Moucey RR, Roach JM, Cameron IJ, de Mestre AMMultivariable analysis to investigate factors associated with day 14 to 16 pregnancy rate in Thoroughbred mares on an intensively managed UK stud farm. Journal of Equine Veterinary Science. 2023 June; 125:104795. 

 

DOI: 10.1016/j.jevs/2023.104795

 

 

Jaworska J, Tobolski D, Kahler A, Woctawek-Potocka I, de Mestre AMEndometrial immune cells at the time of implantation in mares–preliminary results. Journal of Equine Veterinary Science. 2023 June; 104769. 

 

DOI: 10.1016/j.jevs.2023.104769

 

 

Roach JM, Foote AK, Verheyen KL, Bryan J, Smith KC, de Mestre AMGross and histological features associated with umbilical cord torsion in equine abortions. Journal of Equine Veterinary Science. 2023 June; 104815. 

 

DOI: 10.1016/j.jevs/2023.104815

 

 

Shilton CA, Townsend SS, Kahler A, Wathes CD, Castaneda C, Ghosh S, Davis BW, Raudsepp T, de Mestre AMMicrodeletions on chromosomes 2 and 20 are associated with equine early pregnancy loss. Journal of Equine Veterinary Science. 2023 June; 125. 

 

DOI: 10.1016/j.jevs.2023.104784

 

 

Thompson RE, Meyers MA, Magee C, de Mestre AMAntczak DF, Hollinshed FK. Evaluation of chorionic girdle organoids for ultrastructure and equine Chorionic Gonadotropin production. Journal of Equine Veterinary Science. 2023 June; 125.

 

DOI: 10.1016/j.jeva.2023.104788

 

 

Tuffour I, Amuzu S, Bayoumi H, Surtaj I, Parrish C, Willand-Charnley R. Early in vitro evidence indicates that deacetylated sialic acids modulate multi-drug resistance in colon and lung cancers via breast cancer resistance protein. Front Oncol. 2023;13:1145333. 

 

DOI: 10.3389/fonc.2023.1145333

PMID: 37377914

PMC10291187

 

 

López-Astacio RAAdu OF, Lee H, Hafenstein SL, Parrish CRThe Structures and Functions of Parvovirus Capsids and Missing Pieces: the Viral DNA and Its Packaging, Asymmetrical Features, Nonprotein Components, and Receptor or Antibody Binding and Interactions. J Virol. 2023 Jul 27;97(7):e0016123. 

 

DOI: 10.1128/jvi.00161-23

PMID: 37367301

PMCID: PMC10373561

 

May 2023

 

Thompson RE, Meyers MA, Palmer J, Veeramachaneni DNR, Magee C, de Mestre AMAntczak DF, Hollinshead FK. Production of Mare Chorionic Girdle Organoids That Secrete Equine Chorionic Gonadotropin. Int J Mol Sci. 2023 May 31;24(11).

 

DOI: 10.3390/ijms24119538 

PMID: 37298490

PMCID: PMC10253530

 

 

Mouncey R, Arango-Sabogal JC, de Mestre AM, Verheyen KL. Incidence of disease, injury and death in Thoroughbred foals and yearlings on stud farms in the UK and Ireland. Vet Rec. 2023 Jun-Jan 17;192(12):e2994. 

 

DOI: 10.1002/vetr.2994

PMID: 37183185

 

April 2023

 

Vogels CBF, Brackney DE, Dupuis AP 2nd, Robich RM, Fauver JR, Brito AF, Williams SC, Anderson JF, Lubelczyk CB, Lange RE, Prusinski MA, Kramer LD, Gangloff-Kaufmann JL, Goodman LB, Baele G, Smith RP, Armstrong PM, Ciota AT, Dellicour S, Grubaugh ND. Phylogeographic reconstruction of the emergence and spread of Powassan virus in the northeastern United States. Proc Natl Acad Sci U S A. 2023 Apr 18;120(16):e2218012120.

 

DOI: 10.1073/pnas.2218012120

PMID: 37040418

PMCID: PMC10120011

 

March 2023

 

Zehr JD, Kosakovsky Pond SL, Millet JK, Olarte-Castillo XA, Lucaci AG, Shank SD, Ceres KM, Choi A, Whittaker GRGoodman LB, Stanhope MJ. Natural selection differences detected in key protein domains between non-pathogenic and pathogenic feline coronavirus phenotypes. Virus Evol. 2023;9(1):vead019. 

 

DOI: 10.1093/ve/vead019

PMID: 37038392

PMCID: PMC10082545

 

Rathbone P, Arango-Sabogal JC, De Mestre AM, Scott CJ. Antimicrobial resistance of endometrial bacterial isolates collected from UK Thoroughbred mares between 2014 and 2020. Vet Rec. 2023 Mar;192(5):e2591.

 

DOI: 10.1002/vetr.2591

PMID: 36809533

 

 

Chien YA, Alford BK, Wasik BRWeichert WSParrish CR, Daniel S. Single Particle Analysis of H3N2 Influenza Entry Differentiates the Impact of the Sialic Acids (Neu5Ac and Neu5Gc) on Virus Binding and Membrane Fusion. J Virol. 2023 Mar 30;97(3):e0146322.

 

DOI: 10.1128/jvi.01463-22

PMID: 36779754

PMCID: PMC10062150

 

 

Chivu AG, Abuhashem A, Barshad GRice EJ, Leger MM, Vill AC, Wong W, Brady R, Smith JJ, Wikramanayake AH, Arenas-Mena C, Brito IL, Ruiz-Trillo I, Hadjantonakis AK, Lis JT, Lewis JJDanko CGEvolution of promoter-proximal pausing enabled a new layer of transcription control. Res Sq. 2023 Mar 24. 

 

DOI: 10.21203/rs.3.rs-2679520/v1

PMID: 36993251

PMCID: PMC10055653

 

February 2023

 

Prasanna Weeratunga, Rebecca M. Harman and Gerlinde R. Van de WalleInduced pluripotent stem cells from domesticated ruminants and their potential for enhancing livestock production. Front Vet Sci. 2023 Feb 20;10:1129287.

 

DOI.org/10.3389/fvets.2023.1129287

PMID: 36891466 

PMCID: PMC9986305

 

 

Laura E. M. Dunn, Fang Lu, Chenhe Su, Paul M. Lieberman and Joel D. Baines. Reactivation of Epstein-Barr Virus from Latency Involves Increased RNA Polymerase Activity at CTCF Binding Sites on the Viral Genome. J Virol. 2023 Feb 28;97(2):e0189422. 

 

DOI: 10.1128/jvi.01894-22

PMID: 36744959 

PMCID: PMC9972995

 

 

Nagaraja R Thirumalapura, Julia Livengood, John Beeby, Weihua Wang, Erin L Goodrich, Laura B Goodman, Erdal Erol, Deepanker Tewari. Improved molecular detection of Neorickettsia risticii with a duplex real-time PCR assay in the diagnosis of Potomac horse fever. J Vet Diagn Invest. 2023 Jan;35(1):62-66.

 

DOI: 10.1177/10406387221135184

PMID: 36373552 

PMCID: PMC9751466

 

January 2023

 

Thirumalapura NR, Livengood J, Beeby J, Wang W, Goodrich EL, Goodman LB, Erol E, Tewari D. Improved molecular detection of Neorickettsia risticii with a duplex real-time PCR assay in the diagnosis of Potomac horse fever. J Vet Diagn Invest. 2023 Jan;35(1):62-66.

 

DOI: 10.1177/10406387221135184

PMID: 36373552

PMCID: PMC9751466

 

 

McBride SE, Lieberthal BA, Buttke DE, Cronk BD, De Urioste-Stone SM, Goodman LB, Guarnieri LD, Rounsville TF, Gardner AM. Patterns and Ecological Mechanisms of Tick-Borne Disease Exposure Risk in Acadia National Park, Mount Desert Island, Maine, United States. J Med Entomol. 2023 Jan 12;60(1):62-72. 

 

DOI: 10.1093/jme/tjac152

PMID: 36271802

 

 

López-Astacio RA, Adu OF, Goetschius DJ, Lee H, Weichert WS, Wasik BR, Frueh SP, Alford BK, Voorhees IEH, Flint JF, Saddoris S, Goodman LB, Holmes EC, Hafenstein SL, Parrish CRViral capsid, antibody, and receptor interactions: experimental analysis of the antibody escape evolution of canine parvovirus. bioRxiv. 2023 Jan 19.

 

DOI: 10.1101/2023.01.18.524668

PMID: 36711712

PMCID: PMC9882321

 

 

Zehr JD, Kosakovsky Pond SL, Millet JK, Olarte-Castillo XA, Lucaci AG, Shank SD, Ceres KM, Choi A, Goodman LB, Stanhope MJ. Natural selection differences detected in key protein domains between non-pathogenic and pathogenic feline coronavirus phenotypes. Virus Evol. 2023;9(1):vead019.

 

DOI: 10.1093/ve/vead019

PMID: 37038392

PMCID: PMC10082545

 

 

Goodrum F, Lowen AC, Lakdawala S, Alwine J, Casadevall A, Imperiale MJ, Atwood W, Avgousti D, Baines J, Banfield B, Banks L, Bhaduri-McIntosh S, Bhattacharya D, Blanco-Melo D, Bloom D, Boon A, Boulant S, Brandt C, Broadbent A, Brooke C, Cameron C, Campos S, Caposio P, Chan G, Cliffe A, Coffin J, Collins K, Damania B, Daugherty M, Debbink K, DeCaprio J, Dermody T, Dikeakos J, DiMaio D, Dinglasan R, Duprex WP, Dutch R, Elde N, Emerman M, Enquist L, Fane B, Fernandez-Sesma A, Flenniken M, Frappier L, Frieman M, Frueh K, Gack M, Gaglia M, Gallagher T, Galloway D, García-Sastre A, Geballe A, Glaunsinger B, Goff S, Greninger A, Hancock M, Harris E, Heaton N, Heise M, Heldwein E, Hogue B, Horner S, Hutchinson E, Hyser J, Jackson W, Kalejta R, Kamil J, Karst S, Kirchhoff F, Knipe D, Kowalik T, Lagunoff M, Laimins L, Langlois R, Lauring A, Lee B, Leib D, Liu SL, Longnecker R, Lopez C, Luftig M, Lund J, Manicassamy B, McFadden G, McIntosh M, Mehle A, Miller WA, Mohr I, Moody C, Moorman N, Moscona A, Mounce B, Munger J, Münger K, Murphy E, Naghavi M, Nelson J, Neufeldt C, Nikolich J, O'Connor C, Ono A, Orenstein W, Ornelles D, Ou JH, Parker J, Parrish C, Pekosz A, Pellett P, Pfeiffer J, Plemper R, Polyak S, Purdy J, Pyeon D, Quinones-Mateu M, Renne R, Rice C, Schoggins J, Roller R, Russell C, Sandri-Goldin R, Sapp M, Schang L, Schmid S, Schultz-Cherry S, Semler B, Shenk T, Silvestri G, Simon V, Smith G, Smith J, Spindler K, Stanifer M, Subbarao K, Sundquist W, Suthar M, Sutton T, Tai A, Tarakanova V, tenOever B, Tibbetts S, Tompkins S, Toth Z, van Doorslaer K, Vignuzzi M, Wallace N, Walsh D, Weekes M, Weinberg J, Weitzman M, Weller S, Whelan S, White E, Williams B, Wobus C, Wong S, Yurochko A. Virology under the Microscope-a Call for Rational Discourse. J Virol. 2023 Feb 28;97(2):e0008923.

 

DOI: 10.1128/jvi.00089-23

PMID: 36700640

PMCID: PMC9972907

 

December 2022

 

Jonathan W Villanueva, Lawrence Kwong, Teng Han, Salvador Alonso Martinez, Michael T Shanahan, Matt Kanke, Lukas E Dow, Charles G Danko, Praveen Sethupathy. Comprehensive microRNA analysis across genome-edited colorectal cancer organoid models reveals miR-24 as a candidate regulator of cell survival. BMC Genomics. 2022 Dec 1;23(1):792. 

 

DOI: 10.1186/s12864-022-09018-1 

 

PMID: 36457077

PMCID: PMC9716731

 

November 2022

 

Sonsiray Alvarez Narvaez, Zhenyu Shen, Lifang Yan, Brianna L S Stenger, Laura B Goodman, Ailam Lim, Ruth H Nissly, Meera Surendran Nair, Shuping Zhang, Susan Sanchez. Optimized conditions for Listeria, Salmonella and Escherichia whole genome sequencing using the Illumina iSeq100 platform with point-and-click bioinformatic analysis. PLoS One. 2022 Nov 30;17(11):e0277659.

 

DOI: 10.1371/journal.pone.0277659

PMID: 36449522

PMCID: PMC9710801 

 

 

Nating Wang, Zhong Wang, Charles G. Danko and Tinyi Chu. Mapping Transcription Regulation with Run-on and Sequencing Data Using the Web-Based tfTarget Gateway. Methods Mol Biol. 2023;2599:215-226. 

 

DOI: 10.1007/978-1-0716-2847-8_15

  • PMID: 36427152

 

 

 

Mason C Jager, Joy E Tomlinson, Caitlin E Henry, Megan J Fahey, Gerlinde R Van de Walle. Prevalence and pathology of equine parvovirus-hepatitis in racehorses from New York racetracks. Virol J. 2022 Nov 1;19(1):175. 

 

DOI: 10.1186/s12985-022-01901-3

PMID: 36320007

PMCID: PMC9628030

 

 

Jessika-M V Cavalleri, Orsolya Korbacska-Kutasi, Agnès Leblond, Romain Paillot, Nicola Pusterla, Eike Steinmann, Joy TomlinsonEuropean College of Equine Internal Medicine consensus statement on equine flaviviridae infections in Europe. J Vet Intern Med.  2022 Nov;36(6):1858-1871.

 

DOI: 10.1111/jvim.16581. Epub 2022 Nov 11.

PMID: 36367340

PMCID: PMC9708432

 

 

Laura E M Dunn, Claire H Birkenheuer, Rachel Dufour and Joel D Baines. Immediate Early Proteins of Herpes Simplex Virus Transiently Repress Viral Transcription before Subsequent Activation. J Virol. 2022 Nov 23;96(22):e0141622. 

 

DOI: 10.1128/jvi.01416-22.

PMID: 36300939

PMCID: PMC9683018

 

October 2022

 

Kelly L. Sams, Chinatsu Mukai, Brooke A. Marks, Chitvan Mittal, Elena Alina Demeter, Sophie Nelissen, Jennifer K. Grenier, Ann E. Tate, Faraz Ahmed & Scott A. CoonrodDelayed puberty, gonadotropin abnormalities and subfertility in male Padi2/Padi4 double knockout mice. Rep Bio Endoc. 17 Oct 2022. Volume 20, Article number: 150.

 

DOI: 10.1186/s12958-022-01018-w

 

 

Joy E. Tomlinson, Gerlinde R. Van de Walle. Nasal transmission of equine parvovirus hepatitis.J Vet Med. 17 Oct 2022

 

DOI: 10.1111/jvim.16569

PMID: 36250682 

PMCID: PMC9708389

 

 

James L. Miller, Matt Kanke, Gat Rauner, Kimaya M. Bakhle, Praveen Sethupathy & Gerlinde R. Van de WalleComparative Analysis of microRNAs that Stratify in vitro Mammary stem and Progenitor Activity Reveals Functionality of Human miR-92b-3p. J Mammary Gland Biol Neoplasia. . 2022 Oct 3.

 

PMID: 36190643

 

DOI: /10.1007/s10911-022-09525-7

 

September 2022

 

Kaiping Deng, Steffen Uhlig, Laura B Goodman, Hon S Ip, Mary Lea Killian, Sarah M Nemser, Jodie Ulaszek, Shannon Kiener, Matthew Kmet, Kirstin Frost, Karina Hettwer, Bertrand Colson, Kapil Nichani, Anja Schlierf, Andriy Tkachenko, Mothomang Mlalazi-Oyinloye, Andrew Scott, Ravinder Reddy, Gregory H Tyson. Second round of an interlaboratory comparison of SARS-CoV2 molecular detection assays used by 45 veterinary diagnostic laboratories in the United States. J Vet Diagn Invest. 2022 Sep;34(5):825-834

 

DOI: 10.1177/10406387221115702

PMID: 35983593

PMCID: PMC9446291

 

 

Consuelo B. Correa Sierra, Luis M. SchangOn the Sensitivity of the Virion Envelope to Lipid Peroxidation. Virology.  20 Sept 2022.

 

DOI: 10.1128/spectrum.03009

 

 

Tom J Divers, Joy E Tomlinson, Bud C Tennant. The history of Theiler's disease and the search for its aetiology. Vet J. 2022 Sep;287:105878.

 

DOI: 10.1016/j.tvjl.2022.105878

PMID: 35907440

 

August 2022

 

Yidan Zhang, Young W. Choi, Buket Demir, Fatemeh Ekbataniamiri, M. L. Fulton, Mingli Ma, Luis M. Schang, Laura Purevdorj-Gage and Mingyu Qiao. Novel chlorine-extending polymer coating with prolonged antiviral activity against SARS-CoV-2. App Micro Int’l. 15 Aug 2022

 

https://DOI.org/10.1111/lam.13804

PMID: 35965454

 

David W. McKellar, Madhav Mantri, Meleana Hinchman, John S.L. Parker, Praveen Sethupathy, Benjamin D. Cosgrove, Iwijn De Vlaminck. In situ polyadenylation enables spatial mapping of the total transcriptomeBioRXiv. 21 Apr 2022. Pre-print

 

DOI: 10.1101/2022.04.20.488964v1

 

 

Rebecca M. Harman, Katherine A. Churchill, Sonia Parmar and Gerlinde R. Van de Walle. Mesenchymal stromal cells isolated from chicken peripheral blood secrete bioactive factors with antimicrobial and regenerative properties. Front. Vet. Sci. 24 Aug 2022. 

 

DOI: 10.3389/fvets.2022.949836

PMID: 36090169

PMCID: PMC9449329

 

 

James Miller, Matt Kante, Gat Rauner, Kimaya M. Bakhle, Praveen Sethupathy, Gerlinde Van de Walle. Comparative analysis of microRNAs that stratify in vitro mammary stem and progenitor activity reveals functionality of human miR-92b-3p.Journal of Mammy Gland Biology & Neoplasia. 9:949836.

 

DOI: 10.1007/s10911-022-09525-7

PMID: 36190643

 

 

Madhav Mantri, Meleana M. Hinchman, David W. McKellar, Michael F. Z. Wang, Shaun T. Cross, John S. L. Parker, Iwijn De Vlaminck, Spatiotemporal transcriptomics reveals pathogenesis of viral myocarditis. BioRXiv. Pre-print

 

DOI: 10.1101/2021.12.07.471659

 

 

Kaiping DengSteffen UhligLaura B GoodmanHon S IpMary Lea KillianSarah M NemserJodie UlaszekShannon KienerMatthew KmetKirstin FrostKarina HettwerBertrand ColsonKapil NichaniAnja SchlierfAndriy TkachenkoMothomang Mlalazi-OyinloyeAndrew ScottRavinder ReddyGregory H Tyson Second round of an interlaboratory comparison of SARS-CoV2 molecular detection assays used by 45 veterinary diagnostic laboratories in the United StatesJ Vet Diagn Invest. 2022 Aug 18;10406387221115702.

 

DOI: 10.1177/10406387221115702. 

PMID: 35983593

 

July 2022

 

Ola Diebold, Victoria Gonzalez, Luca Venditti, Colin Sharp, Rosemary A Blake, Wenfang Tan, Joanne Stevens, Sarah Caddy, Paul Digard, Alexander Borodavka, Eleanor Gaunt. Using Species a Rotavirus Reverse Genetics to Engineer Chimeric Viruses Expressing SARS-CoV-2 Spike Epitopes. J Virol. 2022 Jul 27;96(14):e0048822. 

 

DOI: 10.1128/jvi.00488-22

PMID: 35758692

PMCID: PMC9327695

 

 

James L. Miller, Arianna P. Bartlett, Rebecca M. Harman, and Gerlinde R. Van de Walle. Induced mammary cancer in rat models: pathogenesis, genetics, and relevance to female breast cancer. Journal of Mammary Gland Biology and Neoplasia. 29 July 2022.

 

DOI: 10.1007/s10911-022-09522-w

PMID: 35904679

 

 

Shao-Pei Chou, Adriana K Alexander, Edward J Rice, Lauren A Choate, Charles G Danko. Genetic dissection of the RNA polymerase II transcription cycle. Elife. Vol. 11, p. e78458.

 

DOI: 10.7554/eLife.78458

PMID: 35775732

PMCID: PMC9286732

 

 

Charles Danko, Gilad Barshad, James Lewis, Alexandra Chivu, Abderhman Abuhashem, Nils Krietenstein, Edward Rice, Oliver J Rando, Anna-Katerina Hadjantonakis. RNA polymerase II and PARP1 shape enhancer-promoter contacts. Research Square. 26 Jul 2022. Pre-print.

 

DOI: https://DOI.org/10.21203/rs.3.rs-1851612/v1