Many dogs show significant signs of stress when having an appointment at the vet. We want to assess if clonidine can reduce stress in dogs during these visits.

We wish to enroll about 22 dogs in this study. This is a double-blinded, placebo-controlled study. During one visit, your dog will receive clonidine. During the other visit, your dog will receive the placebo. Neither you nor the veterinarian will know which treatment your dog receives during each visit.

Eligibility: Dogs must be evaluated by the Behavior service at the Cornell University Hospital for Animals (CUHA) to determine eligibility.

Compensation: All costs of the study, including the screening visit, will be paid for by the study.

Owner Responsibilities: You will be asked to bring your dog to the CUHA for 2 visits. Each visit will be approximately one hour. There will be at least one week between each visit. All other responsibilities will be explained to you at the screening visit.

Principal Investigators: Sun Kim, DVM, DACVB, PhD, Kate Anderson, DVM, DACVB, Yeonhee Lee, DVM

Contact/Schedule an Appointment: Please contact the behavior service or clinical trials coordinator at 607.253.3060, or email vet-research@cornell.edu. Your referring veterinarian may also contact the hospital to refer your pet.