David Gludish, PhD, DVM
Our research focuses on the heterogeneity of tissue macrophages, and the mechanisms in myeloid cells that govern their roles as targets, reservoirs or drivers of viral infection and pathology. Our studies employ novel live cell reporter tools, single-cell and next generation sequencing, mouse genetics and human hematopoietic stem/progenitor cells to study replication of HIV and SARS-CoV2 in live cells and tissues of humans and humanized mice. Combining comparative histopathology with more sophisticated cellular and molecular analyses, our aim is to robustly model human viral infections with a focus on macrophage ontogeny and lung alveolar pathology.
- B.Sc. (Hons) McMaster University 2004
- M.Sc. Mcmaster University 2007
- PhD. Cornell University 2017
- DVM Cornell University 2020
- Postdoctoral Associate, Cornell University (Russell Lab) 2020.
Awards and Honors