Holger Sondermann, PhD

Department of Molecular Medicine


Holger Sondermann's Lab

Department of Molecular Medicine
Cornell University College of Veterinary Medicine

C4-175 Veterinary Medical Center
Ithaca, NY 14853

Office: 607.253.3318
Lab: 607.253.3609
Email: hs293@cornell.edu

Research Interest

Cells respond to a large variety of signals using only a limited set of signaling modules which are organized in complex networks. The activity of these signaling switches is spatially and temporally regulated, and this regulation governs normal development and cellular homeostasis. Consequently, uncontrolled activation is a hallmark of many diseases such as cancer. It is therefore not surprising that the cell has intricate regulatory mechanisms in place to control signal transduction. Our lab is interested in deciphering the basic regulatory principles in signal transduction networks on a molecular level using a combination of X-ray crystallography, biophysical and cellular approaches. We focus on two main areas of research: Bacterial signaling controlling biofilm formation and pathogenicity, and membrane trafficking in eukaryotes.


  • PhD, Biochemistry, Max Planck Institute of Biochemistry, 2001
  • Diploma in Biology, Biology, University of Cologne, 1997
  • Abitur, Kaiserin-Theophanu-Gymnasium , 1992

Biography/Professional Experience

  • 2016-Present, Professor, College of Veterinary Medicine, Cornell University
  • 2010-2016, Associate Professor, College of Veterinary Medicine, Cornell University
  • 2006-2010, Robert N. Noyce Assistant Professor in Life Science and Technology, College of Veterinary Medicine, Cornell University
  • 2005-2010, Assistant Professor, College of Veterinary Medicine, Cornell University
  • 2001-2005, Postdoctoral Work, University of California, Berkeley
  • 2001-2001, Postdoctoral Work, The Rockefeller University


Awards and Honors

  • 2008-2013, PEW Scholar in Biomedical Sciences
  • 2010, Pfizer Animal Heath Award for Research Excellence
  • 2007, Exceptional Merit Award, College of Veterinary Medicine, Cornell
  • 2002-2005, Leukemia & Lymphoma Society Career Development Fellowship
  • 2002, Young Investigator Research Award 2002, MPI of Biochemistry