Toshi Kawate, PhD
- Ph D, Cellular, Molecular, Biophysical Studies, Columbia University, 2005
- MS, Medical Science, Osaka University, 2000
- BS, Biology, Osaka University, 1998
- 2009-2011, Postdoctoral Fellow, NINDS, Laboratory of Dr. Kenton Swartz, National Institutes of Health
- 2005-2009, Postdoctoral Fellow, The Vollum Institute, Laboratory of Dr. Eric Gouaux, Oregon Health and Science University
- 2001-2005, Graduate Student, Department of Biochemistry and Biophysics, Laboratory of Dr. Eric Gouaux, Columbia University
- 2000-2001, Research Assistant, Department of Internal Medicine, Laboratory of Dr. Thomas Sato. UT Southwestern Medical Center at Dallas
- Karasawa, A., Michalski, K., Mikhelzon, P., and Kawate, T. (2017) The P2X7 receptor forms a dye-permeable pore independent of its intracellular domain but dependent on membrane lipid composition. eLife 6:e31186.
- Karasawa A. and Kawate, T. (2017) Expression and Purification of a Mammalian P2X7 Receptor from Sf9 insect Cells. Bio Protoc. 7(17).
- Kawate T. (2017) P2X Receptor Activation. Adv Exp Med Biol. June 22; PMID:28639248 DOI:10.1007/5584_2017_55
- Karasawa A. and Kawate, T. (2016) Structural basis for subtype-specific inhibition of the P2X7 receptor. eLife 5:e22153.
- Michalski, K. and Kawate, T. (2016) Carbenoxolone inhibits Pannexin1 channels through interactions in the first extracellular loop. J Gen Physiol. 147(2):165-74.
- Richards, M.J., Hsia, C.Y., Singh, R.R., Haider, S.H., Kumpf, J.M., Kawate, T., and Daniel, S. (2016) Membrane protein mobility and orientation preserved in supported bilayers created directly from cell plasma membrane blebs. Langmuir. 32(12):2963-74.
Awards and Honors
- 2015-2017, Young Investigators Grants, The Human Frontier Science Program,
- 2011-2014, NIH Pathway to Independence Award (R00)
- 2010, NIH Fellows Award for Research Excellence
- 2010, NIH Pathway to Independence Award (K99)
- 2002, Biophysical Society