Metabolic Disease

The use of rodent (and other) models for understand the genetics and pathology of a wide range of human diseases is a major mission in the Department. Besides the long-standing interest in diseases of the cardiovascular system and calcium imaging modalities for cardiac and other tissues, spearheaded by our former Chair and now Provost, Michael Kotlikoff, our Department has a growing interest in aging and in metabolic disease. Praveen Sethupathy moved his lab to Biomedical Sciences in June 2017. His lab focuses on how microRNAs function in the liver and intestine, with particular focus on the role of these regulatory RNAs in the molecular etiology of complex diseases, including diabetes, hyperlipidemia, liver cancer, and inflammatory bowel diseases.