Cassandra M B Guarino

Cassandra Guarino

Department of Population Medicine and Diagnostic Sciences

Assistant Professor of Practice


Department of Population Medicine and Diagnostic Sciences
Cornell University College of Veterinary Medicine
Ithaca, NY 14853

Office: 607.253.4343

Research Interest

Dr. Guarino is interested in the development of novel serologic assays for the diagnosis of infection with viral and bacterial pathogens in companion and production animals. Of particular interest is the diagnosis of commonly known and emerging vector-borne diseases.


Ph.D. Comparative Biomedical Sciences: minors in Biomedical Engineering and Molecular and Integrative Physiology, Cornell University (2013)
B.S. Animal Science/Agricultural Technology, Cornell University (2004)

Biography/Professional Experience

2016-present Extension Associate, Animal Health Diagnostic Center, Cornell University
2013-2015 Postdoctoral Associate, Biomedical Engineering, Cornell University
2013 Postdoctoral Associate, Chemical and Biomolecular Engineering, Cornell University
2004-2006 Medical Technologist, Animal Health Diagnostic Center, Cornell University


  1. Watkins HC, Pagan CL, Childs HR, Posada S, Chau A, Rios J, Guarino C, DeLisa MP, Whittaker GR and Putnam D. (2017) Long-term single dose protection against H1N1 influenza A in BALB/c mice through controlled release of M2e-containing recombinant outer membrane vesicles. Vaccine. Epub ahead of print.
  2. Guarino C, Asbie S, Rohde J, Glaser A, Wagner B. (2017) Vaccination of horses with Lyme vaccines for dogs induces short-lasting antibody responses. Vaccine. 35(33):4140.
  3. Rappazzo CG and Watkins HC, Guarino C, Chau A, Lopez JL, DeLisa MP, Leifer CA, Whittaker GR, Putnam D. (2016) Recombinant M2e outer membrane vesicle vaccines protect against lethal influenza A challenge in BALB/C mice. Vaccine. 34(10):1252.
  4. Ollis A, Chai Y, Natarajan A, Perregaux E, Jaroentomeechai T, Guarino C, Smith J, Zhang S, DeLisa MP.  (2015) Substitute sweetners: diverse bacterial oligosaccharyltransferases with unique N-glycosylation site preferences. Scientific Reports. 5:15237
  5. Mansell TJ, Guarino C, DeLisa MP. (2013) Engineered genetic selection links in vivo protein folding and stability with asparagine-linked glycosylation. Biotechnol J. 8(12):1445.
  6. Guarino C, DeLisa MP. (2012) A prokaryote-based cell-free translation system that efficiently synthesizes glycoproteins. Glycobiology 22(5):596.
  7. Fisher AC, Haitjema CH, Guarino C, Celik E, Endicott C, Reading CA, Merrit JH, Ptak AC, Zhang S, DeLisa MP. (2011) Production of secretory and extracellular N-linked glycoproteins in Escherichia coli. AEM 77:871.
  8. Celik E, Fisher AC, Guarino C, Mansell TJ, DeLisa MP. (2010) A filamentous phage display system for N-linked glycoproteins. Prot Sci. 19:2006

Awards and Honors

2010-2012 NSF GK-12 fellowship, CLIMB, Cornell University
2002-2004 Morrison Award, Cornell University

Professional/Academic Affiliations

American Association of Veterinary Laboratory Diagnosticians
Society for Glycobiology