The Clinical Pathology Laboratory is in the Department of Population Medicine and Diagnostic Sciences, and is also a unit of the Animal Health Diagnostic Center at Cornell University. The Laboratory is staffed by four clinical pathologists, all of whom are board-certified by the American College of Veterinary Pathologists, a laboratory manager, multiple medical technologists and veterinary technicians, and three administrative assistants. We also have three training positions including two clinical pathology residents and one intern. We have a high-volume, high-quality laboratory equipped with state-of-the-art analyzers. We provide diagnostic testing and professional consultation services to the Cornell University Hospital for Animals, to researchers affiliated with Cornell University and to private veterinary practitioners and researchers throughout New York, the USA, and worldwide.
The clinical pathology section is an academic unit with three mandates:
- Professional diagnostic service: We are committed to performing high-quality, timely, comprehensive, and accurate laboratory testing of animal specimens in the areas of hematology, clinical chemistry, diagnostic cytology, immunology, and urinalysis. As part of this service, we provide professional consultation for our laboratory results.
- Education: We are dedicated to educating current and future veterinarians in clinical pathology through our residency program, interactive case-based lectures, laboratories and seminars, elective laboratory rotations for students, interns and residents, and web-based educational resources (see eClinPath).
Research: We are committed to contributing to the advancement of knowledge in clinical pathology through investigative research. Our faculty and residents are actively involved in clinical applied research, which is a vital component of our residency training program. Current research areas of interest are:
- Hematopoietic neoplasia, such as leukemia and lymphoma
- Thrombotic disorders in animals
- Hematologic disorders, including iron deficiency anemia and immune-mediated hemolytic anemia
Clinical Pathology performs testing for a variety of researchers and contract laboratories. We can create customized panels, consisting of specific tests for research projects. We also provide consultation on study design (if desired), how to submit samples (with examples of request forms), and guidance on optimal sample collection, labeling, and shipping.
For all research projects, the project leader (or designated representative) must contact our laboratory manager before any samples can be accepted for analysis. We will require the following information when setting up a research account:
- Contact information
- Manner of result reporting - we can send your results by fax, email or regular mail
- Species to be tested
- Tests required
- Project schedule including start date, ending date, anticipated dates of submission, and estimated numbers of animals
- Any special handling or storage requirements – this may be test dependent.
The laboratory manager will use this information to formulate a plan so your research project will be performed in the most efficient manner possible.
"Immunohistochemical Labeling of Low-Density Lipoprotein Receptor and Scavenger Receptor Class B Type 1 Are Increased in Canine Lymphoma." Ceres K, Fitzgerald H, Quiznon KS, McDonough S, Behling-Kelly E. Frontiers in Veterinary Science. 2018;5:340. doi: 10.3389/fvets.2018.00340. Epub 2019 Jan 11.
"Pharmacokinetics and Pharmacodynamics of an Oral Formulation of Apixaban in Horses After Oral and Intravenous Administration. " Serpa PBS, Brooks MB, Divers T, Ness S, Birschmann I, Papich MG, Stokol T. Frontiers in Veterinary Science. 2018 Dec;5:304. doi: 10.3389/fvets.2018.00304. Epub 2018 Dec 4.
"Pharmacokinetics of Human Recombinant C1-Esterase Inhibitor and Development of Anti-Drug Antibodies in Healthy Dogs." Wong C, Muguiro DH, Lavergne S, Behling-Kelly E, Goggs R. Vet Immunol Immunopathol. 2018 Sep;203:66-72. doi: 10.1016/j.vetimm.2018.08.006. Epub 2018 Aug 23.
"A Commercial Soy-Based Phospholipid Emulsion Accelerates Clot Formation in Normal Canine Whole Blood and Induces Hemolysis in Whole Blood from Normal and Dogs with Inflammatory Leukograms." Behling-Kelly EL, Wakshlag J. J Vet Emerg Crit Care (San Antonio). 2018 May;28(3):252-260. doi: 10.1111/vec.12716. Epub 2018 Apr 6.
"Influence of Multiple Reuse and Resterilization Cycles on the Performance of a Bipolar Vessel Sealing Device (LigaSure) Intended for Single Use." Kuvaldina A, Hayes G, Sumner J, Behling-Kelly E. Vet Surg. 2018 Sep 4. doi: 10.1111/vsu.12948. [Epub ahead of print]
"What is Your Diagnosis? Mandibular Mass In a Cat.: Newman AW, Asakawa MG, Stokol T. Vet Clin Pathol. 2018 Sep;47(3):501-502. doi: 10.1111/vcp.12617. Epub 2018 May 14. No abstract available.
"Subcutaneous Administration of Low-Molecular-Weight Heparin to Horses Inhibits Ex Vivo Equine Herpesvirus Type 1-Induced Platelet Activation." Stokol T, Serpa PBS, Brooks MB, Divers T, Ness S. Front Vet Sci. 2018 May 28;5:106. doi: 10.3389/fvets.2018.00106. eCollection 2018.
"Dogs with Acute Myeloid Leukemia or Lymphoid Neoplasms (large cell lymphoma or acute lymphoblastic leukemia) May Have Indistinguishable Mediastinal Masses on Radiographs." Epperly E, Hume KR, Moirano S, Stokol T, Intile J, Erb HN, Scrivani PV. Vet Radiol Ultrasound. 2018 Sep;59(5):507-515. doi: 10.1111/vru.12622. Epub 2018 May 3.
"Method Comparison and Validation of a Prototype Device for Measurement of Ionized Calcium Concentrations Cow-Side Against a Point-of-Care Instrument and a Benchtop Blood-Gas Analyzer Reference Method." Neves RC, Stokol T, Bach KD, McArt JAA. J Dairy Sci. 2018 Feb;101(2):1334-1343. doi: 10.3168/jds.2017-13779. Epub 2017 Dec 14.
"A Retrospective Review of Acute Myeloid Leukaemia in 35 Dogs Diagnosed by a Combination of Morphologic Findings, Flow Cytometric Immunophenotyping and Cytochemical Staining Results (2007-2015)." Davis LL, Hume KR, Stokol T. Vet Comp Oncol. 2018 Jun;16(2):268-275. doi: 10.1111/vco.12377. Epub 2017 Dec 14.
"Diagnostic performance of cytology for assessment of hepatic lipid content in dairy cattle."
Fry MM, Yao B, Ríos C, Wong C, Mann S, McArt JAA, Nydam DV, Leal Yepes FA, Viesselmann L, Geick A, Goldin K, Jordan A, Behling-Kelly E. J Dairy Sci. 2018 Feb;101(2):1379-1387. doi: 10.3168/jds.2017-12897. Epub 2017 Dec 14.
"In vitro Inhibition of Canine Complement-Mediated Hemolysis." Hernandez DM, Goggs R, Behling-Kelly E. J Vet Intern Med. 2018 Jan;32(1):142-146. doi: 10.1111/jvim.14871. Epub 2017 Nov 24.
"Development of a plasminogen activator inhibitor (PAI-1) assay and comparison of plasma PAI-1 activity in hyperlipidemic/dyslipidemic dogs with either hyperadrenocorticism or diabetes mellitus, and healthy dogs" by Wong CJ, Koch M, Behling-Kelly EL. in Res Vet Sci. 2017 Apr;111:1-8. doi: 10.1016/j.rvsc.2016.11.004. Epub 2016 Nov 8.
"Acute leukemia in six horses (1990-2012)" by Barrell EA, Asakawa MG, Felippe MJB, Divers TJ, Stokol T. in J Vet Diagn Invest. 2017 Jul;29(4):529-535. doi: 10.1177/1040638717707724. Epub 2017 May 3.
" Dogs with Acute Myeloid Leukemia Have Clonal Rearrangements in T and B Cell Receptors" by Stokol T, Nickerson GA, Shuman M, Belcher N. in Front Vet Sci. 2017 May 31;4:76. doi: 10.3389/fvets.2017.00076. eCollection 2017.
"Unfractionated and Low-Molecular-Weight Heparin and the Phosphodiesterase Inhibitors, IBMX and Cilostazol, Block Ex Vivo Equid Herpesvirus Type-1-Induced Platelet Activation" by Stokol T, Serpa PBS, Zahid MN, Brooks MB. in Front Vet Sci. 2016 Nov 17;3:99. eCollection 2016. Erratum in: Front Vet Sci. 2017 Feb 10;4:10.
"Evaluation of procoagulant tissue factor expression in canine hemangiosarcoma cell lines” by Lauren Witter and colleagues in Dr. Stokol’s laboratory in the American Journal of Veterinary Research 2017 doi: 10.2460/ajvr.78.1.69.
"Atypical chronic myeloid leukemia in a German Shepherd Dog”, a case report in the Journal of Veterinary Diagnostic Investigation by Drs. Marino (University of Pennsylvania), Tran and Stokol, 2017 Feb 1:1040638716689581. doi: 10.1177/1040638716689581.