Comparative Oral Oncology Laboratory (COOL)
Welcome to the Comparative Oral Oncology Laboratory. We are a group of researchers dedicated to advancing health for both humans and companion animals, with a focus on oral tumor biology and treatment. We are firm believers in bringing the most advanced scientific approaches to bear to tackle oral oncology head-on, and are deeply dedicated to multi-disciplinary collaborative science as a necessary and productive means to further our knowledge, and develop new cures for cancer.
Current Events @ COOL
New Publication – Single Cell RNA-sequencing reveals unique neurological phenotype in ameloblastomas
The Sethupathy lab has recently discovered a unique phenotype in ameloblastoma tumors. These tumors are traditionally very difficult to differentiate from squamous cell carcinomas, which becomes a concern when choosing treatment options. With these findings, currently available as a pre-print in bioarxiv, we hope to resolve some of those difficulties. This may also lead to improved treatment options for ameloblastomas.
Trainee Spotlight
Arly Camila Armas Jimenez of the Evans Lab
Recently, Cami presented her research at the International Conference on Canine and Feline Genetics and Genomics (ICCFGG), where scientists and clinicians from around the world gather to advance research on inherited diseases, cancer, behavior, morphology, and evolutionary biology in companion animals. Speaking in the Cancer Genetics session, Camila shared her work on canine oral squamous cell carcinoma, highlighting how whole-genome sequencing is helping researchers better understand the tumors' mutational landscape and identify potential therapeutic targets.
Cami is a PhD candidate who earned her master's degree in Animal Science from Oklahoma State University and her bachelor's degree in Biotechnology from Universidad de las Fuerzas Armadas – ESPE in her home country of Ecuador.