Medical Genetics and Genomics
| Faculty | Research Area(s) |
|---|---|
 Doug Antczak |
Pregnancy immunology; immunogenetics; equine immunology |
| Mitochondrial disease; obesity and metabolic disease | |
 Adam Boyko |
Genomic investigation of dogs as a model of genetic disease and evolutionary genetics |
 Ilana Brito |
Pioneering new methods to detect horizontal gene transfer in natural microbial communities to understand the rate and triggers of horizontal gene transfer; the impact of human microbiome diversity on world global health issues - lab |
 Nicolas Buchon |
Host/microbe relationships and control of intestinal stem cell behavior in homeostasis and disease - lab |
 Jonathan Butcher |
Mechanobiology of development; developmental signaling reactivation in adult cardiovascular diseases; tissue engineering and regeneration - lab |
 Yung-Fu Chang |
Mechanisms of infection, particularly leptospira and salmonella |
| Postpartum ovarian and uterine health; epidemiology; regenerative medicine; microfluidics and assisted reproductive techniques - lab | |
 Ruth Collins |
Pharmacology; cancer cell biology; small GTPase regulation of intracellular traffic and cellular growth control - lab |
 Scott Coonrod |
Reproductive physiology; molecular and cellular physiology; epigenetic reprogramming during the egg-to-embryo transition; mechanisms by which specific histone modifications are dynamically regulated during hormone-dependent gene transcription in breast cancer cells |
 Charles Danko |
Medical genetics and genomics and cancer biology research |
|
|
genetic and epigenetic mechanisms of chromosome inheritance and aging during meiosis and early development. |
 Erin Daughterity |
(Minor Member) As a trained, American College of Laboratory Animal Medicine (ACLAM) board certified veterinarian, Dr. Erin Daugherity has a strong interest in animal models of disease, the humane use of animals used in teaching and research, and applying the 3 R’s (reduce, refine, replace) to the use of animals in research. |
 Mandi de Mestre |
processes for a healthy pregnancy and delivery of a neonate, pathologies that compromise pregnancy. Improve diagnostics and treatments for pregnancy conditions, primarily in the mare |
 Matthew DeLisa |
Molecular biotechnology; protein biogenesis and folding pathways; protein engineering - lab |
 Callum Donnelly |
Theriogenology, equine genomics/ epigenomics, pregnancy/placental physiology, Vitamin E |
 Jacquelyn Evans
|
hereditary diseases in dogs to identify genetic variants contributing to disease development - lab |
 Maria Julia Bevilaqua Felippe |
Cellular and molecular mechanisms involved in B-cell response; neonatal immunology and response to vaccination; immunomodulation using biologic response modifiers; cancer immunotherapy; characterization of primary and secondary immunodeficiencies - lab |
| Pathogen discovery and surveillance, with focus areas on tick-borne disease and antimicrobial resistance; exploring the underlying mechanisms of infectious disease emergence and identifying biomarkers to detect and prevent emerging threats to humans and animals | |
 Chun Han |
mechanisms of dendrite morphogenesis and neurodegeneration using Drosophila sensory neurons as a model system - lab |
 Elizabeth Johnson |
bioactive lipids shape host-microbe interactions; host-microbe molecule exchange and bioactive lipids in infant nutrition |
 Natasza Kurpios |
Tissue morphogenesis; cell shape and architecture; organ development; gut morphogenesis; mammary gland biology; breast cancer - lab |
 Colleen Lau
|
NK cells adaptive features to explore immune memory in context of classic antigen-dependent and antigen-independent memory responses. Multi-omic approaches with genetic mouse models to interrogate in vivo, in vitro, and in silico to generate an immune memory program. - Lab |
 Brian Lazzaro |
The evolutionary and functional genetics of insect-pathogen interactions - lab |
 Siu Sylvia Lee |
Molecular genetics of aging; signaling pathways of nutrient sensing; molecular basis of stress response - lab |
 David Lin |
Axon guidance; neurodevelopment; epilepsy; autism; genomics - lab |
 Eirene Markenscoff-Papadimitriou
|
gene-regulatory mechanisms that generate diversity during brain development; probe function of human genetic variants linked to autism - lab |
 Motoko Mukai |
Endocrine Disrupting Compounds (EDCs); neuroendocrine regulation; reproductive, developmental, and metabolic health effect of toxic compounds found in food - lab |
 Alexander Nikitin |
Stem cells and cancer; pathogenesis of ovarian and prostate cancers; modeling of human disease in genetically modified mice and human organoids - lab |
 Zeribe Nwosu |
Cancer metabolism and therapeutic opportunities |
 Kimberly O'Brien |
Calcium metabolism and bone health; control of maternal/fetal nutrient; partitioning and cellular mineral transport; micronutrient status in international settings; development of mass spectrometric methodology; pediatric bone health; pregnancy and mineral metabolism in adolescents - lab |
 John Parker |
A new single cell sequencing approach; RNA-seq, Ribo-seq and scRNA-seq. |
 Shu-Bing Qian |
Translational control of gene expression; signaling pathways in stress response; protein quality control in metabolic diseases - lab |
 Richa Sardana
|
Membrane protein trafficking and quality control mechanisms - lab |
 Luis Schang |
Role of cellular protein, lipids, and glycans play in viral infection |
 John Schimenti |
Genetics of reproduction and germ cell development; cancer genetics; meiosis; DNA repair; genome manipulation in mice; functional genomics - lab |
 Praveen Sethupathy |
Functional genomics; gene regulation; molecular genetics; gastrointestinal physiology; stem cell biology; metabolic disease - lab |
 Paul Soloway |
Epigenetic regulatory mechanisms in mammals; Chromatin changes associated with neuropathy using single cell analyses - lab |
 Rory J. Todhunter |
Canine hip dysplasia; genetic linkage analysis; osteoarthritis |
 Tudorita Tumbar |
Basic cellular and molecular mechanisms implicated in cell fate choice and stem cell activity within tissues - lab |
 Meng Wang |
We use molecular biology, genetics and animal models to dissect how our metabolism gives rise to chemicals that damage our DNA- Wang Lab |
 Gary R. Whittaker |
Pathogenesis of influenza viruses, corona viruses and arena viruses; host range and receptors; activation of membrane fusion; macrophage- and neurotropism; anti-viral therapeutics; diagnostic tests; virus-bacteria co-infections - lab |
 Haiyuan Yu |
The Yu group performs research in the broad areas of Network Systems Biology. We use integrated computational-experimental systems biology approaches to determine protein interactions and complex structures on the scale of the whole cell. In particular, we focus on protein-protein and gene regulatory networks and seek to understand how such intricate systems evolve and how their perturbations lead to human diseases, especially autism spectrum disorder and cancer. |
 Mariana Wolfner |
Genetic, molecular, developmental, and evolutionary studies of seminal proteins' functions in fertility, and of mechanisms of egg activation and initiation of embryogenesis; investigate conserved phenomena in reproductive biology, using primarily the Drosophila model system - lab |
