Cancer Biology
| Faculty | Research Area(s) |
|---|---|
 Parminder Basran |
Radiation Dosimetry and Treatment Planning; Medical Image Processing and Analysis; and Medical Physics Training and Education. I have keen interests in machine learning methods in radiation oncology, radiomics, and stereotactic ablative radiation therapies and hypo-fractionation. |
 Nicolas Buchon |
Host/microbe relationships and control of intestinal stem cell behavior in homeostasis and disease - lab |
 Richard A. Cerione |
Signal transduction growth factor receptors; protein structure; drug design and chemical biology; signaling cues that direct cell proliferation, differentiation and development - lab |
 Paula E. Cohen |
Etiology of spontaneous birth defects in mammals; mechanisms of meiotic recombination; DNA repair proteins in meiosis and recombination; germ cell development; ovarian development - lab |
 Ruth Collins |
Pharmacology; cancer cell biology; small GTPase regulation of intracellular traffic and cellular growth control - lab |
 Scott Coonrod |
Reproductive physiology; molecular and cellular physiology; epigenetic reprogramming during the egg-to-embryo transition; mechanisms by which specific histone modifications are dynamically regulated during hormone-dependent gene transcription in breast cancer cells |
 Brian R. Crane |
Metalloenzyme structure and catalysis; protein electron transfer; nitric oxide enzymology; bacterial chemotaxis; circadian clock photo sensors - lab |
 Charles Danko |
Medical genetics and genomics and cancer biology research |
 Erin Daughterity
|
As a trained, American College of Laboratory Animal Medicine (ACLAM) board certified veterinarian, Dr. Erin Daugherity has a strong interest in animal models of disease, the humane use of animals used in teaching and research, and applying the 3 R’s (reduce, refine, replace) to the use of animals in research. |
 Matthew DeLisa |
Molecular biotechnology; protein biogenesis and folding pathways; protein engineering - lab |
 Anushka Dongre |
Epithelial-Mesenchymal Transition as a driver of resistance to anti-tumor immunity - lab |
 Gerald E. Duhamel |
Mechanisms of infectious diseases with particular emphasis on molecular mechanisms of bacterial infections in animal models of human diseases; host-pathogen relationships |
 Jacquelyn Evans |
hereditary diseases in dogs to identify genetic variants contributing to disease development - lab |
 Claudia Fischbach-Teschl |
Tissue-engineered model systems for analysis of microenvironmental conditions fundamental to cancer pathogenesis and therapy - lab |
 Kelly Hume |
Cancer biology; veterinary oncology; clinical oncology; molecular oncology; DNA damage; chemosensitivity and novel therapeutics |
 Glenn Jackson
|
My research interests include creating systems to evaluate and improve the welfare of research animals, and the development and refinement of animal models of human disease |
 Shaoyi Jiang
|
(a) Immunology of nanomaterials and implantable materials and (b) safe and targeted delivery of mRNAs and DNAs for cancer immunotherapies/vaccines and neurological diseases |
|
Aims to better understand the signal transduction events that occur following engagement of the T cell antigen receptor; study more globally the molecular events important for immune cell development, differentiation and function |
|
 Natasza Kurpios |
Tissue morphogenesis; cell shape and architecture; organ development; gut morphogenesis; mammary gland biology; breast cancer - lab |
 Jan Lammerding |
Cellular biomechanics; mechanotransduction; cell migration; muscular dystrophy and cancer cell biology - lab |
| The laboratory is currently focused on further advancing the novel 3D organ-on-chip systems, as well as developing both cellular and molecular tools and in vivo models, to better understand the mechanisms through which cells regulate their response to biological and mechanical cues - lab | |
 Cynthia Leifer |
Understanding innate immunity from the receptors that detect microbes to how innate immune cells react to changes in their environment during inflammatory processes - lab |
 Maurine Linder |
Regulation of cell signaling by protein lipidation |
 Andrew Miller |
Anatomic pathology; small and large animal neuropathology; CNS tumorigenesis; disease diagnostics; stem cell pathology - lab |
 Alexander Nikitin |
Stem cells and cancer; pathogenesis of ovarian and prostate cancers; modeling of human disease in genetically modified mice and human organoids - lab |
 Robert Oswald |
Ion channel receptor/ligand interactions; NMR and molecular dynamics; molecular neurobiology and biophysics; neurotransmitter receptors and signal transduction |
 Richa Sardana
|
membrane protein trafficking and quality control mechanisms - lab |
 Luis Schang |
Role of cellular protein, lipids, and glycans play in viral infection |
 John Schimenti |
Genetics of reproduction and germ cell development; cancer genetics; meiosis; DNA repair; genome manipulation in mice; functional genomics - lab |
| The Simmons lab focuses on the role that lipids play in the regulation of inflammatory and other immunological processes in the tumor microenvironment. Using 3-Dimensional bioprinting technology, we are developing novel patient-derived in vitro tumor models for testing various therapeutic approaches in non-small cell lung carcinoma. | |
 Praveen Sethupathy |
Functional genomics; gene regulation; molecular genetics; gastrointestinal physiology; stem cell biology; metabolic disease - lab |
 Carolyn Sevier |
Signaling of cellular oxidative stress; molecular mechanisms used by cellular pathways that sense and signal redox imbalances within the cell |
 Marcus Smolka
|
Cell signaling and genome maintenance; DNA replication stress; phosphproteomics |
 Tudorita Tumbar |
Basic cellular and molecular mechanisms implicated in cell fate choice and stem cell activity within tissues - lab |
 Gerlinde Van de Walle |
Veterinary viral pathogenesis; mesenchymal stem cell biology and regenerative medicine; mammary stem cell biology and carcinogenesis - lab |
 Meng Wang |
We use molecular biology, genetics and animal models to dissect how our metabolism gives rise to chemicals that damage our DNA- Wang Lab |
 Robert S. Weiss |
Molecular mechanisms for the maintenance of genomic stability; cellular responses to DNA damage; mouse models of human cancer - lab |
 Andrew C. White |
Cancer biology; stem cell biology; biochemistry and cell biology - lab |
 Andrew Yen |
Leukemia; cell growth and differentiation; oncogenes/genetics - lab |
