Infection and Immunity
| Faculty | Research Area(s) |
|---|---|
 Hector Aguilar-Carreno |
Entry, egress, and interactions of enveloped viruses with host cells, with emphasis on emerging paramyxoviruses, vaccine and antiviral strategies - lab |
 Craig Altier |
Infection/agent; molecular basis of Salmonella pathogenesis; the genetic and environmental control of epithelial cell invasion |
 Douglas Antczak |
Immunity/host; pregnancy immunology; immunogenetics; equine immunology |
 Avery August |
Immunity/host; regulation of T-cell activation, development and function; T-cell differentiation; mast cell function and eosinophil function - lab |
 Gary Blissard |
Infection/agent; understanding the biology and pathology of viral infections and interactions in insect cells - lab |
 Dwight Bowman |
Infection/agent; soil transmitted parasites, parasites of wildlife, visceral larva migrans, host response to soil transmitted pathogens, detection of soil transmitted parasites |
 Ilana Brito
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Pioneering new methods to detect horizontal gene transfer in natural microbial communities to understand the rate and triggers of horizontal gene transfer; the impact of human microbiome diversity on world global health issues - lab |
 Nicolas Buchon |
Host/microbe relationships and control of intestinal stem cell behavior in homeostasis and disease - lab |
 Sarah Caddy |
understanding the protective activity of non-neutralising antibodies; unravel the negative activities of antiviral antibodies; maternal antibodies - lab |
 James W. Casey |
Infection/agent; molecular virology; retrovirology |
 Pamela Chang |
Immunity/host; host/microbe interactions; gut microbiome - lab |
 Yung-Fu Chang |
Infection/agent; mechanisms of infection, particularly leptospira and salmonella |
 Joshua Chappie |
Structural biology; biophysics; protein biochemistry; bacterial pathogenesis and defense systems; infection/agent; intracellular trafficking; nucleotide-driven molecular machines; molecular membrane remodeling; protein-nucleic acid interactions |
| Cellular and molecular medicine; developmental and reproductive biology; infectious diseases; population medicine and epidemiology; structural and functional biology - lab | |
 Theodore Clark |
Infection/agent; cutaneous immunity; host-parasite interaction; DNA vaccines; genetic factors underlying resistance to infectious disease |
 Aimee Colbath |
therapeutic interventions for musculoskeletal disease including osteoarthritis, fracture repair and tendon/ligament disease |
 Ruth Collins |
Infection/agent; pharmacology; cancer cell biology; small GTPase regulation of intracellular traffic and cellular growth control - lab |
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Protein redox chemistry; electron-transfer reactions; mechanisms of signal transduction; circadian clocks; protein photosensors; bacterial chemotaxis; receptor signaling; nitric oxide enzymology; metallobiochemistry - lab |
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Application of epidemiologic approaches to investigate the ecology and transmission of Salmonella and other foodborne pathogens among a wide variety of hosts |
|
 Matthew DeLisa |
Infection/agent; molecular biotechnology; protein biogenesis and folding pathways; protein engineering - lab |
| To understand the molecular mechanisms underlying virus-host interactions, focusing on the mechanisms underlying viral immune evasion that contribute to virus virulence and disease pathogenesis - Lab | |
 Mariana Diel de Amorim |
equine theriogenology; equine maternal recognition of pregnancy; equine endometritis |
 Tobias Doerr |
Cell envelope biology of Gram-negative pathogens, antibiotic resistance, tolerance and mechanism of action; microbial stress responses - lab |
 Anushka Dongre |
Epithelial-Mesenchymal Transition as a driver of resistance to anti-tumor immunity - lab |
 Gerald E. Duhamel |
Infection/agent; mechanisms of infectious diseases with particular emphasis on molecular mechanisms of bacterial infections in animal models of human diseases; host-pathogen relationships |
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Immunity/host; cellular and molecular mechanisms involved in B cell response; neonatal immunology and response to vaccination; immunomodulation using biologic response modifiers; cancer immunotherapy; characterization of primary and secondary immunodeficiencies - lab |
|
 Julia Finkelstein |
To elucidate the role of iron, vitamin B12, and folate in the etiology of anemia and adverse pregnancy outcomes, and inform the development of interventions to improve the health of mothers and young children |
 Andrew Flyak
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human antibody response to viral pathogens; use immunologic and biochemistry assays and use structural biology techniques to “see” how antibodies bind and neutralize viral pathogens - Lab |
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Regulation of immunity at tissue sites of infection and autoimmunity, immune imaging, intravital multiphoton microscopy |
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 Mason Jager
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host-pathogen interactions with a specific emphasis on viral pathogenesis; association of novel viruses with clinical disease; use traditional pathology, molecular virology, and cell biology to study virus distribution, tissue tropism, and host factors required for disease progression |
 Shaoyi Jiang
|
design and development of functional zwitterionic materials for biomedical and engineering applications |
 Toshi Kawate |
Structures and mechanisms of membrane proteins that regulate extracellular signaling |
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Aims to better understand the signal transduction events that occur following engagement of the T cell antigen receptor; study more globally the molecular events important for immune cell development, differentiation and function |
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 Colleen Lau
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NK cells adaptive features to explore immune memory in context of classic antigen-dependent and antigen-independent memory responses. Multi-omic approaches with genetic mouse models to interrogate in vivo, in vitro, and in silico to generate an immune memory program. - Lab |
 Brian Lazzaro |
The evolutionary and functional genetics of insect-pathogen interactions - lab |
| The laboratory is currently focused on further advancing the novel 3D organ-on-chip systems, as well as developing both cellular and molecular tools and in vivo models, to better understand the mechanisms through which cells regulate their response to biological and mechanical cues - lab | |
 Cynthia Leifer |
Immunity/host; understanding innate immunity from the receptors that detect microbes to how innate immune cells react to changes in their environment during inflammatory processes - lab |
 Sabine Mann |
Metabolic diseases and insulin signaling; nutrition; epidemiology; metabolic and nutritional immunology |
 Mandy McGeachy
|
we are working to understand how Th17 cells develop and are influenced to be ‘good’ or ‘bad’ in their functions - lab |
 Saurabh Mehta |
Global health (active research projects in India, East Africa, and Latin America); infectious disease epidemiology, particularly HIV, Tuberculosis, and neglected tropical diseases; nutritional interventions and nutritional modulation of the immune response - lab |
 John Parker |
Cell biology/biochemistry with a focus on cellular translation and the effect of viral infection; Virology; Feline Calicivirus; mammalian orthoreoviruses; virus-host interactions; effect of viral infection on host cell translation; use of viruses for treatment of cancer; virus entry; broadly neutralizing antibodies; innate immune response to viruses |
 Colin Parrish |
Emergence of new viral diseases in dogs; canine influenza viruses: emergence, spread, and ways to stop the spread; how parvovirus can pass from species to species - lab |
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We are generally interested in genomic stability and chromosome evolution, especially how these are impacted by mobile DNA elements. We have a special interest in molecular mechanisms mobile elements capable of moving between positions in the genome called transposons use to limit damage to the host and maximize the process of horizontal transfer. |
 Raina Plowright
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studied pathogens that spill over from animals to people, the dynamics of zoonotic pathogens in wildlife populations, and pathogens that threaten wildlife conservation |
 Brian Rudd |
Developmental immunology; host response to infection - lab |
 David Russell |
Infection/agent; the biology of intracellular infection with emphasis on mycobacteria |
| bacterial cell envelope structure, structure-function relationships - lab | |
 Luis Schang |
Role of cellular protein, lipids, and glycans play in viral infection |
 Kenneth Simpson |
Host pathogen interactions in inflammatory bowel disease and Helicobacter infection of the gastrointestinal - lab |
 Jeongmin Song |
Host-pathogen interactions; bacterial toxins; Salmonella Typhi; bacterial pathogens - lab |
 Brian VanderVen |
Physiology of the intracellular pathogen M. tuberculosis - lab |
 Gerlinde Van de Walle |
Veterinary viral pathogenesis; mesenchymal stem cell biology and regenerative medicine; mammary stem cell biology and carcinogenesis - lab |
 Bettina Wagner |
Immunity/host; antibody mediated immune mechanisms in infectious disease and vaccination; allergic diseases; neonatal tolerance and allergy predisposition; strategies to develop allergy treatments - lab |
 Gary R. Whittaker |
Pathogenesis of influenza viruses, coronaviruses and arenaviruses; host range and receptors; activation of membrane fusion; macrophage- and neuro-tropism; anti-viral therapeutics; diagnostic tests; virus-bacteria co-infections - lab |
 Martin Wiedmann |
Infection/agent; molecular pathogenesis of food-borne and zoonotic bacterial diseases |
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Milk harvesting process; support science-based development and on-farm implementation of innovative machine technologies and milking routines; epidemiological studies that deliver data to improve profitability and sustainability |
| Faculty | Research Area(s) |
|---|---|
 Rodman Getchell |
Molecular diagnostics and emerging diseases of fish; target animal safety studies for new aquaculture therapeutants and chemicals |
| Population and clinical studies; Pathogen discovery and surveillance, with focus areas on tick-borne disease and antimicrobial resistance; exploring the underlying mechanisms of infectious disease emergence and identifying biomarkers to detect and prevent emerging threats to humans and animals | |
 Yrjö Gröhn |
Population and clinical studies; veterinary epidemiology; production medicine; public health; epidemiological and economic methods; risk analysis, communication and policy |
 Renata Ivanek |
Epidemiology and ecology of infectious and foodborne diseases; mathematical modeling; spatial epidemiology; risk assessment; public health |
 Hussni Mohammed |
Population and clinical studies; epidemiology of infectious diseases; quantitative and analytical epidemiology; epidemiological risk assessment and analysis; veterinary public health and food safety; production medicine |
 Daryl V. Nydam |
Population and clinical studies; epidemiology of food security/safety issues related to dairy production medicine; study of economically important infectious diseases, particularly zoonoses; subclinical diseases of peraparturient cattle and reproductive efficacy |
 Heidi Reesink |
Comparative and translational orthopedics; metabolism and musculoskeletal disease; osteoarthritis; regenerative medicine |
 Lorin Warnick |
Population and clinical studies; dairy cattle epidemiology; pre-harvest food safety; Salmonellosis in cattle; infectious disease |
